Voltadol 140mg 10 Medicated Adhesive Dressings

Voltadol (140 Mg 10 Medicated Adhesive Dressings)
Active ingredient: Diclofenac

Voltadol is available in the form of medicated adhesive dressings for the treatment of local pain and inflammation. It is mainly used for acute injuries such as sprains and bruises, providing localized relief thanks to diclofenac, which acts as an anti-inflammatory and analgesic.

PHARMACOKINETICS
Diclofenac is slowly absorbed through the skin when used in adhesive dressings, providing a continuous and sustained release with a plasma concentration of approximately 3 ng/ml. Its affinity with plasma proteins is high (99%). The metabolism and elimination of topically applied diclofenac are similar to those of oral administration.

INDICATIONS
Symptomatic treatment of processes with inflammation and/or acute pain, such as:

• Contusion or sprain caused by twisting.

DOSAGE
Voltadol Dressings

• Apply a medicated adhesive bandage to the painful area once a day.
• The maximum daily dose is one adhesive dressing, even if there is more than one injured area to be treated. Only one painful area should be treated at a time.

ADVICE TO THE PATIENT

• Do not cut the dressings into pieces.
• Do not use for more than 7 days without consulting a doctor.

PRECAUTIONS

• Photosensitivity reactions : Diclofenac may cause photosensitivity reactions. It is advisable not to expose the treated area to the sun or ultraviolet light for at least one day.
• Systemic reactions : The risk of systemic reactions with topical diclofenac is low, although it may increase if applied to damaged areas (dermatitis, burns, wounds) or used with occlusive dressings. Dosage recommendations should be followed in patients with asthma, history of peptic ulcer, renal or cardiac insufficiency, and hypertension.

PREGNANCY

• Safety in animals : No adverse effects on prenatal, perinatal or postnatal development of offspring were observed.
• Human safety : Approximately 10% of the topical dose is absorbed systemically, resulting in considerably lower bioavailability compared to oral administration. There are no adequate and well-controlled studies in humans with topical diclofenac, but systemic use of diclofenac has been associated with fetal toxic effects in late pregnancy.
  • First two trimesters : Its use is accepted only if the benefits outweigh the possible risks and there are no safer therapeutic alternatives.
  • Third trimester : Its use is contraindicated, since diclofenac has been associated with delayed delivery and cardiopulmonary and renal adverse effects in the fetus, such as premature closure of the ductus arteriosus and pulmonary hypertension, acute renal failure and oligohydramnios. It may also increase bleeding time in the mother.

LACTATION

• Safety in humans : Diclofenac is excreted in breast milk, although it is considered to have no significant adverse effects on the breast-fed infant. However, due to the lack of sufficient data, a decision must be made whether to discontinue breast-feeding or to discontinue therapy, taking into account the benefit of breast-feeding for the child and the benefit of therapy for the mother.

ADVERSE REACTIONS

• Dermatological : Frequent (1-10%) local reactions at the application site, such as itching, skin irritation, erythema, rashes, sometimes accompanied by pustules or papules.
• Allergic : Uncommon (0.1-1.0%) hypersensitivity reactions, contact dermatitis; isolated cases of anaphylaxis, angioedema and photosensitivity reactions.
  In case of significant absorption, systemic adverse reactions typical of diclofenac may occur.

OVERDOSE

• Symptoms : Given the route of administration, overdose symptoms are unlikely to occur, but accidental ingestion or improper application could cause systemic adverse effects.
• Treatment : In case of accidental ingestion, gastric lavage should be performed and symptomatic treatment applied according to medical criteria.

Package Leaflet Voltadol 140mg 10 Medicated Adhesive Dressings