Rino Ebastel 10/120 Mg 7 Capsules

Rino Ebastel (10/120 Mg 7 Capsules)

You can buy Rino Ebastel 10/120 mg 7 capsules online from UK, Austria, Belgium, Cyprus, Estonia, Finland, France, Germany, Greece, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands (Nederlands), Portugal, Sweden (Sverige), Slovakia and Slovenia. 

Rino-Ebastel 10 mg / 120 mg is a double-acting product, nasal decongestant and antihistamine, composed of pseudoephedrine and ebastine, which helps reduce the symptoms of seasonal allergic rhinitis when accompanied by nasal congestion by prolongedly inhibiting the induced effects by histamine. 
With a single take a day and without intervening in your daily rhythm.

ACTION AND MECHANISM

- Rino Ebastel is a combination of a [NASO / FARINGEO DESCONGESTIONANT] with a selective [HISTAMINERGIC ANTAGONIST (H-1)], from the piperidine group.

INDICATIONS

- [NASAL CONGESTION]. Rino Ebastel is indicated for the treatment of nasal congestion that accompanies cadres of [ALLERGIC RHINITIS], such as [SEASONAL ALLERGIC RHINITIS] or [PERENNE ALLERGIC RHINITIS], and [VASOMOTORY RHINITIS] associated with [COMMON COLD].

DOSAGE OF RINO EBASTEL

DOSAGE: 
- Adults, oral: 1 capsule of Rino Ebastel every 24 hours. In severe cases, 1 Rino Ebastel capsule can be administered every 12 hours. 
- Children, oral: 
* Children 12 years or older: 1 capsule of Rino Ebastel every 24 hours. In severe cases, 1 Rino Ebastel capsule can be administered every 12 hours. 
* Children under 12 years: Safety and efficacy have not been evaluated. 
The duration of treatment should be limited to the symptomatic phase, not usually extending for more than 10 days in case of allergic or vasomotor rhinitis or 3 days in rhinitis associated with the common cold. 

RULES FOR THE CORRECT ADMINISTRATION OF RINO EBASTEL

It is recommended to administer Rino Ebastel at about the same time every day. If two doses are administered, it will be done with breakfast and dinner.

CONTRAINDICATIONS OF RINO EBASTEL

- Hypersensitivity to any component of the medication. 
- [PORPHYRIA]. H1 antihistamines are not considered safe in these patients. 
- Severe heart disease or uncontrolled diabetes mellitus. 
- Patients in treatments with antidepressants of the MAOI type in the 14 days before starting therapy with pseudoephedrine (See Interactions).

PRECAUTIONS OF RINO EBASTEL

- [RENAL INSUFFICIENCY], [HEPATIC INSUFFICIENCY]. The active substances could accumulate, with the risk of adverse reactions.

- Patients with [DIABETES], [GLAUCOMA], [CARDIOPATIA] ([CORONARY INSUFFICIENCY], [ISCHEMICAL CARDIOPATIA]), [ARTERIAL HYPERTENSION], [HYPERTHROIDISM], [FEOCROMOCITOMA] or [HYPERTHYSIS] PROSTATICS. Pseudoephedrine could aggravate these pictures. In case of serious or decompensated disease, the use of this medicine may be contraindicated (See Contraindications).

- Patients with [ARRITMIA CARDIACA], [BRADICARDIA], [PROLONGATION OF THE QT INTERVAL], [HYPOPOTASEMIA] or in treatment with drugs that affect the QT interval or that inhibit the metabolism of ebastine (See Interactions), at the risk of Torsade from Pointes. Although there have been no cases, it cannot be ruled out that ebastine results in prolongation of the QTc interval at high doses.

- [EPILEPSY]. Some antihistamines may induce the appearance of seizures.

PRECAUTIONS REGARDING EXCIPIENTS OF RINO EBASTEL

- Rino Ebastel contains sucrose. Patients with hereditary [INTRODUCTION TO FRUCTOSE], glucose or galactose malabsorption, or sucrose-isomaltase insufficiency should not take this medication.

PATIENT ADVICE

- It is recommended not to exceed the recommended daily dose. 
- The treatment should be suspended and see a doctor if the symptoms persist for more than five days, if they get worse or if high fever, dizziness, insomnia or nervousness appear. 
- The doctor or pharmacist should be notified if the patient has diabetes, heart disease, hypertension or glaucoma, as well as if he is being treated with any other drug. 
- It is recommended to suspend the treatment at least 24 hours before a surgical intervention and 72 hours before performing allergy skin tests. 

SPECIAL WARNINGS

- It is recommended to periodically monitor blood pressure in hypertensive patients and blood glucose in diabetic patients. 
- It is advisable to distance the intake of MAOI and pseudoephedrine for at least 14 days. 
- It is recommended to monitor the cardiac functionality and the electrocardiogram in patients with heart disease or in those treated with erythromycin, ketoconazole or antiarrhythmic drugs, given the risk of prolongation of the QTc interval.

RINO EBASTEL INTERACTIONS

- Inhalation anesthetics. It could increase the risk of severe ventricular arrhythmias, so it is recommended to discontinue treatment at least 24 hours before surgery. 
- Tricyclic antidepressants. Tricyclic antidepressants may potentiate the vasopressor effects of sympathomimetic amines, leading to hypertensive crises. It is recommended to avoid association. 
- Antihypertensives (beta-blockers, diuretics, guanetidine, methyldopa). Pseudoephedrine may antagonize its effects. Administration with beta-blockers has resulted in hypertensive crises, due to beta blockade. It is recommended to periodically monitor blood pressure. 
- Digoxin. The risk of cardiac arrhythmias associated with pseudoephedrine could be increased. 
- Erythromycin, ketoconazole. They could increase the risk of prolongation of the QT interval due to possible inhibition of ebastine metabolism. It is recommended to extreme precautions. 
- Nerve stimulants (amphetamines, cocaine, xanthines). Nerve stimulation could be enhanced, resulting in intense excitability. 
- Thyroid hormones. There could be a potentiation of the cardiac effects of pseudoephedrine, with risk of arterial hypertension and coronary insufficiency. 
- IMAO. MAOIs could potentiate the effects of pseudoephedrine by inhibition of norepinephrine metabolism, increasing the risk of hypertensive crises and other cardiac phenomena. It is recommended to avoid the administration of this medicine in patients treated with MAOI in the previous 14 days. 
- Levodopa. Increases the risk of cardiac arrhythmias. 
- Nitrates Pseudoephedrine may antagonize the antianginal effects of nitrates, so it is recommended to avoid association. 
- Reserpine. Reserpine may reduce the effects of indirect sympathomimetics such as pseudoephedrine, due to depletion of noradrenergic vesicles. 
- Sympathomimetics. It can produce a potentiation of side effects, both of nervous and cardiovascular origin.

RINO EBASTEL AND PREGNANCY

There have been no adequate and well-controlled clinical trials in humans, so the use of this medication is only accepted in the absence of safer therapeutic alternatives, and provided that the benefits outweigh the possible risks.

RINO EBASTEL AND BREASTFEEDING

Some of the active substances in this medicine are excreted with milk, so it is recommended to stop breastfeeding or avoid administering this medicine.

RINO EBASTEL IN CHILDREN

The safety and efficacy of this medicine in children under 12 years of age have not been evaluated, so its use is not recommended.

RINO EBASTEL IN ELDERLY

The elderly are more susceptible to the side effects of these medications, so caution is recommended.

EFFECTS ON DRIVING

Although very rare, in certain especially sensitive patients, this medication may affect the ability to drive and / or operate machinery. Patients should avoid operating dangerous machinery, including cars, until they are reasonably certain that drug treatment does not adversely affect them.

ADVERSE REACTIONS

The adverse effects of this medicine are, in general, rare at the recommended doses, although they may increase in intensity and severity at higher doses. The most frequent alterations are: 
- Digestive [NAUSEAS], [VOMITOS], [DYSPEPSY], [CONDEMNATION], [DIARRHEA] and [MOUTH DROUGHT]. 
- Neurological / psychological. The appearance of [SOMNOLENCE] and [CEFALEA] is frequent. More rarely [NERVIOSISM], [EXCITABILITY], [INSOMNIUM], [MAREO] or [VERTIGO] may occur. 
- Cardiovascular. [ARRITMIA CARDIACA], with [TAQUICARDIA] and [PALPITACIONES]. It can also occur [ARTERIAL HYPERTENSION] and [BRADICARD] reflects. 
- Allergic / dermatological. [HYPERSENSITIVITY REACTIONS], with [URTICARY] and [EXANTEMATIC ERUPTIONS].

OVERDOSE

Symptoms: Overdose by this medicine may lead to the appearance of neurological symptoms (drowsiness, nervousness, restlessness, hallucinations, respiratory depression) and / or cardiovascular (tachycardia, bradycardia, arterial hypertension, palpitations, reflex hypotension). 
Treatment: It is recommended to carry out the usual measures of elimination, with forced emesis and gastric lavage. If absorption of active ingredients has already taken place, it is recommended to keep the patient under surveillance and establish symptomatic treatment.

DOPING

Pseudoephedrine is a prohibited substance during competition.

It is prohibited when its administration results in a concentration in urine greater than 150 mcg / ml.

Detection in a sample during competition of any amount of pseudoephedrine in combination with a diuretic or a masking agent, will be considered an adverse analytical result, unless the athlete has obtained an approved therapeutic use authorization (AUT) for ephedrine, in addition of that granted for the diuretic or masking agent.

It is considered "specific substance" and, therefore, a violation of the rule in which this substance is involved may result in a reduction of sanction provided that the athlete can demonstrate that the use of the specific substance in question was not intended to be Increase your sports performance.

Rino Ebastel leaflet (10/120 Mg 7 Capsules)