Peroxiben 50 Mg/G Topical Gel 60 G

Peroxiben 50 Mg/G Topic Gel 60 G

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ACTION AND MECHANISM

- [ANTIACNEICO]. [ANTIBACTERIAL OF TOPICAL USE] active against Propionibacterium acnes, microorganism involved in acne vulgaris. It is also [QUERATOLITICO] and [ANTISEBORREICO], counteracting hyperkeratinization and excess secretion of sebum associated with acne.

PHARMACOKINETICS

Percutaneous penetration of benzoyl peroxide is low; When applied to the skin, it is completely converted to benzoic acid which is quickly eliminated in urine.

INDICATIONS

- [ACNE VULGAR] of moderate degree.

POSOLOGY

Adults, topical route: Initial treatment: 1-2 applications a day on the affected area, freshly washed and dried. In patients with very sensitive skin, it is advisable to start the treatment with one application a day. 
It is recommended to begin with presentations of lesser concentration to be gradually increased. 
Improvement can be observed at 4-6 weeks, although longer periods may be necessary. 

RULES FOR THE CORRECT ADMINISTRATION

Apply on freshly washed skin and dry a thin film of gel with the fingertips, avoiding the eyes, mouth, nostrils or mucous membranes. If it comes in contact with the eyes, wash immediately with warm water. 
It should not be applied on damaged or eczematous skin, or on cuts or abrasions. 
It can produce discoloration, so it should not come in contact with any dyed material (hair, fabrics).

CONTRAINDICATIONS

- Hypersensitivity to benzoyl peroxide.

PRECAUTIONS

- [WOUNDS]. It should not be applied on damaged or eczematous skin, nor on cuts or abrasions due to the possible risk of absorption. Avoid eyes, mouth, nostrils or mucous membranes. If it comes in contact with the eyes, wash immediately with warm water. 
- [HYPERSENSITIVITY REACTIONS]. If a reaction occurs that suggests sensitivity to any of the components, discontinue the application. 
- Use of cosmetics. Use caution if cosmetics with desquamative, irritating or drying effects are used, since these can enhance the irritative effects of benzoyl peroxide. 
- [PHOTOSENSITIVITY REACTIONS]. Benzoyl peroxide may cause photosensitivity. Avoid excessive exposure to sunlight or UV radiation. It would be advisable to use sunscreens or protective clothing. 
- Avoid contact with eyes, mucous membranes, inflamed or eroded skin and hair. 
- It can bleach hair and dyed or colored fabrics.

PATIENT TIPS

- Avoid applying on damaged skin, eyes and mouth. 
- Avoid getting in contact with hair or dyed fabrics, because it can discolor them. 
- Avoid excessive exposure to the sun or UV radiation. 
- Notify the doctor and / or pharmacist if symptoms of allergic reaction are observed. 
- Use caution if desquamating, irritating or drying cosmetics are used because of the risk of boosting the irritative effect of benzoyl peroxide. 

SPECIAL WARNINGS

- If a reaction that suggests sensitivity to any of the components occurs, interrupt the application.

INTERACTIONS

No interactions have been described and, due to their low absorption, they are not to be expected. However, it would be advisable to avoid co-administration with azelaic acid and desquamative, irritant or drying cosmetics.

PREGNANCY

Category C of the FDA. It is not known if it can cause fetal harm when administered to pregnant women or if it affects reproductive capacity. However, topical administration is usually considered safe for use during pregnancy. Use in pregnant women only if strictly necessary.

LACTATION

It is unknown if this drug is excreted in breast milk and the possible effects on the infant. Precautionary use

CHILDREN

The safety and efficacy of the use of this drug in children under 12 years have not been established. Use not recommended in children under 12 years.

ELDERLY

No specific geriatric information is available.

ADVERSE REACTIONS

In the place of application may appear: 
- [WOUNDS]. [SKIN DRYING], [CUTANEOUS DESCAMATION], [ERITEMA] and occasionally [EDEMA]. 
- [HYPERSENSITIVITY REACTIONS]: [CONTACT DERMATITIS] (burning, stinging and redness). In case of excessive [IRRITATION CUTANEA], remove the product with soap and water, and it should not be applied until the next day.

Prospectus Peroxiben 50 Mg / G Gel Topico 60 G

Technical Sheet Peroxiben 50 Mg / G Gel Topico 60 G