Hibitane 5/5 Mg 20 Tablets To Suck Lemon

Hibitane (5 Mg/5 Mg 20 Tablets To Suck (Lemon Flavor))

Chlorhexidine dihydrochloride 5 mg/ Benzocaine 5 mg

ACTION AND MECHANISM

- Association of local anesthetic type ester and antiseptic. Benzocaine works by blocking sensory receptors in the mucous membranes locally. Chlorhexidine is a broad-spectrum antiseptic with special activity against gram-positives, it also has a fungistatic effect against Candida.

INDICATIONS

- Symptomatic relief of [ORAL INFECTION] and [PHARYNGITIS], which present with pain and without fever (throat irritation, [HOFIA], [HOARENESS], [ORAL THRUSH]).

POSOLOGY

"COMPRESSED"

- Adults and children over 6 years: 1 tablet/2 h. Do not exceed 8 tablets/day.

RULES FOR CORRECT ADMINISTRATION

"COMPRESSED"

Dissolve the tablets slowly in the mouth, without chewing or swallowing.

CONTRAINDICATIONS

- [ALLERGY TO ESTER TYPE LOCAL ANESTHETICS] to PABA or parabens or paraphenylenediamine (a hair dye), or to clohexidine.

- Children under 6 years of age, due to their special sensitivity to the systemic toxicity of benzocaine, which may cause methemoglobinemia.

PRECAUTIONS

- If after two days of treatment, the symptoms worsen or are accompanied by fever, headache, nausea or vomiting, consult your doctor.

ADVICE TO THE PATIENT

- Administration is not recommended in children under 3 years of age (normal and forte mint tablets) or 6 years of age (forte orange-flavored tablets).

- The tablets should not be chewed or swallowed, since their action is local.

- You can permanently color the fillings if the surface or its margins are rough.

- Maintain adequate oral hygiene, with special anti-tartar toothpaste, to reduce the accumulation of anti-tartar and the coloration caused by chlorhexidine.

SPECIAL WARNINGS

- In patients with periodonditis, chlorhexidine causes an increase in supragingival calculus.

INTERACTIONS

Due to the presence of benzocaine, it interferes with:

- Cholinesterase inhibitors: they inhibit the metabolism of the local anesthetic, with the risk of greater systemic toxicity.

- Sulfonamides: the metabolites of benzocaine can antagonize the antibacterial activity of sulfonamides.

PREGNANCY

There are insufficient data on the use of chlorhexidine and benzocaine in pregnant women.

Chlorhexidine: fertility disorders, fetotoxic actions, or peri-postnatal toxicity have not been described in studies carried out with experimental animals.

Benzocaine: No problems have been described with benzocaine in pregnancy.

LACTATION

It is not known whether chlorhexidine is excreted in breast milk. No problems have been described with benzocaine in lactation.

CHILDREN

Due to its benzocaine content, it should not be administered to children under 6 years of age. Children are more sensitive to the systemic toxicity of benzocaine, which can cause methemoglobinemia.

ADVERSE REACTIONS

Adverse effects are generally mild and transient. The most characteristic are:

-Occasionally, brown discoloration of the teeth, fillings, dentures and other oral appliances and the tongue. The coloration of the tongue disappears spontaneously and is not dangerous. The coloration of the teeth is not permanent, it can be removed by oral cleaning. The coloring of fillings can be permanent.

- When starting treatment, temporary taste changes and a burning sensation in the mouth may appear.

- Increased tartar.

- Rare cases of oral irritation have been described due to scaly lesions, sometimes painful (especially in children between 10 and 18 years of age), which is usually temporary, and irritation of the tip of the tongue.

- Also on rare occasions local allergic reactions that, on occasions, were accompanied by nasal congestion, itching, skin rash.

- Burning, itching, swelling or redness in or around the mouth.

Adverse reactions that may arise from the presence of benzocaine are due to excessive dosage or rapid absorption, as well as patient idiosyncrasies, and include contact sensitization and angioedema (due to allergic reaction or contact dermatitis).

OVERDOSE

At the proposed doses, it is difficult for an overdose picture to occur.

- Symptoms: due to chlorhexidine, especially in children, symptoms of alcohol intoxication (slurred speech, drowsiness or unsteady gait). Symptoms due to benzocaine: CNS stimulation (symptoms are blurred or double vision, dizziness, convulsions, ringing in the ears, excitement), followed by CNS depression (drowsiness), cardiovascular system depression, increased sweating, low blood pressure or heartbeat slow or irregular Methemoglobinemia (difficulty breathing, dizziness, fatigue, tiredness, weakness) may also occur.

- Treatment: as far as chlorhexidine is concerned, it is fundamentally symptomatic. Administer oxygen or institute assisted respiration, and for circulatory depression administer a vasoconstrictor and intravenous fluids. Treatment of methemoglobinemia: methylene blue.

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