Flogoprofen 50 Mg/G Topic Gel 100 G (etofenamate)

Flogoprofen 50 Mg/G Topic Gel 100 G (etofenamate) 

You can buy Flogoprofen 100 G (etofenamate) online from UK, Austria, Belgium, Cyprus, Estonia, Finland, France, Germany, Greece, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Portugal, Slovakia and Slovenia. U kunt dormidina kopen in onze online apotheek, wij verzenden naar alle EU-landen.

ACTION AND MECHANISM

The etofenamate is an [ANTIINFLAMMATORY] and [ANALGESIC] non-steroidal, which acts by preventing the synthesis of prostaglandins and other prostanoids, by inhibiting the cyclo-oxygenase involved in inflammatory processes.

PHARMACOKINETICS

- Absorption: The bioavailability of the products containing etofenamate is subject to great inter and intraindividual fluctuations, resulting mainly from the place of administration, hydration of the skin and other factors. After cutaneous administration, bioavailability, that is, the proportion of the dose available systemically, is in the range of other products containing etofenamate (greater than 20%).
- Metabolization and Elimination: Etofenamate is excreted in the form of multiple metabolites (hydroxylation, breakage of ester and ether) and their conjugates, 35% via the kidneys and an extensive proportion through bile and feces. Very likely there is an enterohepatic circulation.

INDICATIONS

Local symptomatic relief of painful or inflammatory conditions, of traumatic or degenerative origin of the joints, tendons, ligaments and muscles ([ARTHRITIS], periarthritis, arthrosynovitis, [TENOSINOVITIS], [CONTUSION], distortions, [LUXATION], meniscal lesions of the knee, [TORTICOLIS], [LUMBALGIA], [ESGUINCE], [CONTRACTURA], [BURSITIS], [CAPSULITIS], [TENDINITIS]).

POSOLOGY

- Use exclusively external cutaneous.
- Adults and children over 12 years: apply 2 to 3 times a day.
- Do not apply more than 7 days in a row without consulting the doctor.


RULES FOR THE CORRECT ADMINISTRATION


- Apply a thin layer of the product to the affected area using a light massage to facilitate penetration.
- Wash your hands after each application.
- Do not apply occlusive bandages.

CONTRAINDICATIONS

- Hypersensitivity to etofenamate or to any of the components of this medicine.
- [ALLERGY TO NSAID], [ALLERGY TO SALICYLATES]: Although the local administration minimizes the risks derived from its systemic use, the topical application, in extended areas of the skin, in open wounds, mucous membranes or eczematous skin, prolonged and With the use of occlusive bandages, can cause systemic effects, so it should be remembered that its use is not recommended in patients who have presented allergic reactions (rhinitis, asthma, pruritus, angioedema, urticaria, shock or other), caused by acid acetylsalicylic or other NSAIDs due to the possibility of cross hypersensitivity.

PRECAUTIONS

WARNINGS ON EXCIPIENTS:

- This medication because it contains dimethyl sulfoxide can cause skin irritation.

 

PATIENT TIPS


- Avoid contact with eyes and mucous membranes.
- Do not use with occlusive bandages or apply simultaneously in the same area as other topical preparations.
- Do not use for prolonged periods of time or in large areas.
- Use only on intact skin, not on open wounds, mucous membranes or eczematous skin.
- Do not expose the treated area to the sun.
- Wash your hands after each application.


SPECIAL WARNINGS


- If the symptoms persist for more than 7 days or irritation or worsening occurs, the clinical situation of the patient should be evaluated.
- A solar exposure of the treated area can cause photosensitivity.

INTERACTIONS

They have not been described in cutaneous use, since very low systemic concentrations of the drug are reached, but it will be assessed if it should be used in conjunction with other topical analgesics.

PREGNANCY

Although cutaneous use systemic absorption is very small, the drug should not be used during pregnancy unless medical criteria, since NSAIDs, especially during the third quarter, can produce dystocia, delay delivery and cause adverse effects on the fetal cardiovascular system , such as the premature closure of the ductus arteriosus.

LACTATION

Although for cutaneous use the systemic absorption is very small, the preparation should not be used during lactation except medical criteria.

ADVERSE REACTIONS

- Moderate local [ERITEMA] (0.1% -1%), [DERMATITIS], [local IRRITATION], [PRURITE] (0.1% -1%) and sensation of [CUTANEOUS IRRITATION] in the area may occur of application, which disappear when treatment is suspended.
- [PHOTOSENSITIVITY REACTIONS] may appear (0.01% -0.1%)
- In the case that symptoms are shown for which no justification is found, the treatment should be suspended and the patient's clinical situation should be re-evaluated.
- Long-term topical administration, over large areas of skin, over open wounds, mucous membranes or eczematous skin, as well as the use of occlusive dressings, may cause the appearance of systemic adverse reactions typical of NSAIDs.

OVERDOSE

- Symptoms: Due to its external use, poisoning is not likely to occur.
In case of accidental ingestion, the symptoms of overdose will be systemic adverse reactions that will depend on the dose ingested and the time elapsed since ingestion.
- Treatment: if accidental ingestion occurs, stomach lavage and symptomatic therapy will be carried out.

 

See leaflet Flogoprofen 50 Mg / G Gel Topico 100 G

See Technical Data Sheet Flogoprofen 50 Mg / G Topical Gel 100 G