Angileptol 30 Mint Eucalyptus Sucking Tablets

Angileptol (30 Mint-Eucalyptus Sucking Tablets)

ACTION AND MECHANISM
Association of local anesthetic type ester, anti-inflammatory and antiseptic. Benzocaine works by blocking sensory receptors on mucous membranes locally. Chlorhexidine is a broad spectrum antiseptic with special activity against gram-positives, it also has a fungistatic effect against Candida. Enoxolone is a compound or, structurally related to corticosteroids, with anti-inflammatory and mineralcorticoid properties.

INDICATIONS
- Local and temporary symptomatic relief of [ORAL INFECTION], [STOMATITIS] and [PHARYNGITIS] mild: [ORAL AFTA], [IRRITATION] of throat due to external aggressive agents such as tobacco, sudden changes in temperature, dust, which occur with pain and no fever.

POSOLOGY
Oropharyngeal use:

- Adults and children over 12 years: 1 tablet / 2-3 h, allowing it to slowly dissolve in the mouth. Maximum dose: 8 tablets / day.

- Children over 6 years: 1 tablet / 4-5 h, allowing it to slowly dissolve in the mouth. Maximum dose 6 tablets / day.

RULES FOR THE CORRECT ADMINISTRATION
- Use oropharyngeal.
- Dissolve slowly in the mouth, without chewing or swallowing.
- Do not use this medicine before meals or before drinking.

CONTRAINDICATIONS
- Allergy to any of the components, [ALLERGY TO LOCAL ANESTHETICS TYPE ESTER] such as PABA, parabens or paraphenylenediamine (a hair dye).

- Children under 6 years of age, due to their special sensitivity to the systemic toxicity of benzocaine, which may cause methemoglobinemia.

PRECAUTIONS
- Chronic or abusive use: due to the mineralcorticoid effect of enoxolone there is a risk of edema formation, loss of potassium and hypertension.

Evaluate the risk-benefit ratio in the following cases:

- Severe trauma to the oral mucosa (increases the absorption of anesthetics).

- Fillings of the incisor teeth: if its surface is rough, there is a risk of permanent staining due to chlorhexidine.

PRECAUTIONS RELATED TO EXCIPIENTS
- This medicine contains sorbitol. Patients with hereditary [FRUCTOSE INTOLERANCE] should not take this medicine.

ADVICE TO THE PATIENT
- If symptoms worsen or persist after 2-3 days, a visit to the doctor may be advised.

- Maintain adequate oral hygiene, special anti-tartar toothpaste, to reduce the discoloration of the teeth caused by chlorhexidine.

INTERACTIONS
- Topical hydrocortisone: possible increase in the topical effect of hydrocortisone (animal studies). It has NOT been determined whether it also increases systemic absorption and toxicity.

Analytical interferences:

- Benzocaine: Possible interference with the diagnostic test for determination of pancreatic function using bentiromide. It is advisable to discontinue the treatment, at least 3 days before the test.

PREGNANCY
Use not recommended due to the mineralcorticoid effects manifested by enoxolone, with high doses during prolonged treatments.

LACTATION
Not recommended use.

CHILDREN
Children are more susceptible to the systemic toxic effects of benzocaine.

ELDERLY
The elderly are especially sensitive during prolonged treatments to the mineralcortioid effects of enoxolone and to the systemic toxicity of benzocaine.

ADVERSE REACTIONS
Adverse effects are generally mild and transient. The most characteristic adverse reactions are:

-Occasionally: staining of the oral surfaces (teeth, gums, tongue, fillings, etc.) that are visible a week after treatment. The coloration of the tongue disappears spontaneously. Tooth discoloration can be removed by oral cleaning. The coloring of the fillings can be permanent. Increased tartar of the teeth, alteration of taste perception.

Enoxolone at high doses (60 mg / day) and during prolonged treatments can cause edema, hypertension and hypokalemia.

-Rarely (<1%): anaphylactoid reaction, burning mouth feeling.

-Exceptionally (<< 1%): methemoglobinemia characterized by cyanosis.

Package Leaflet Angileptol 30 Mint-Eucalyptus Sucking Tablets