Almax 500 Mg 48 Chewable Tablets

Almax (500 Mg 48 Chewable Tablets)

You can buy Almax Chewable Tablets online from UK, United Kingdom (english), Austria, Belgium, Cyprus, Estonia, Finland, France, Germany, Greece, Ireland, Italy (Italia), Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Portugal, Slovakia, Slovenia and Sweden.

ACTION AND MECHANISM

Almax 500 mg Chewable is an Antacid. Almagato is a derivative of aluminum and magnesium, which acts as a non-absorbable antacid, neutralizing hydrochloric acid in the stomach. The increase in gastric pH also reduces the formation and activity of pepsin. In addition, it adsorbs the formed pepsin and adsorbs and neutralizes the bile acids, when these reflux to the stomach.

HOW DO YOU KNOW IF IT'S HEARTBURN?

Acid is produced in the stomach to digest food. When acid leaves the stomach towards the mouth it causes a burning sensation known as heartburn.

Typically, heartburn is caused by...

• It consists of a burning sensation just below or behind the breastbone.
• It may be accompanied by an acidic or sour taste in the mouth.
• It is aggravated by leaning forward, stretching, or lying down, and gets worse after meals.
• It is relieved by taking antacids and erect posture.

PHARMACOKINETICS

Orally:

- Absorption: the absorption of aluminum and magnesium is minimal.

- Excretion: absorbed metal ions are eliminated by the kidneys, while the rest appear in faeces.

ALMAX CHEWABLE TABLETS INDICATIONS

- Symptomatic treatment of [GASTRIC HYPERACIDEZ] in adults and adolescents from 12 years of age.

ALMAX CHEWABLE TABLETS USE AND POSOLOGY

Almax:

- Adults: 1 g / 8 h. If necessary, an additional dose may be given at bedtime. Maximum dose 8 g / 24 h.

- Children and adolescents <18 years old:

* Adolescents from 12 years: as adults.

* Children <12 years: not recommended.

- Elderly: does not require dose readjustment. Avoid prolonged treatments or high doses.

Duration of treatment: avoid treatments over 14 days without medical recommendation.

Oblivion of dose: administer the forgotten dose as soon as possible, unless there is little time left for the next one. Administer the next dose at the usual time. Do not duplicate the next dose.

POSOLOGY IN RENAL INSUFFICIENCY

- Mild to moderate renal insufficiency (CLcr 30-90 ml / min): avoid high doses.

- Severe renal insufficiency (CLcr <30 ml / min): not recommended.

POSOLOGY IN HEPATIC INSUFFICIENCY

No specific dosage recommendations have been made.

RULES FOR THE CORRECT ADMINISTRATION

Almax Chewable tablets: chew or dissolve in the mouth.

Administration with food: administer 30-60 min after meals.

ALMAX CHEWABLE TABLETS CONTRAINDICATIONS

- Hypersensitivity to almagata or any other component of the medication.

- [ALZHEIMER DISEASE]. Aluminum could have a certain relationship with the appearance of this disease.

- Patients with digestive hemorrhages of unknown cause (see Precautions, digestive hemorrhage).

- [HEMORRHOIDS].

- [EDEMA].

- [DIARRHEA]. Magnesium salts may promote diarrhea.

- Gravidic toxemia.

ALMAX CHEWABLE TABLETS PRECAUTIONS

- [RENAL INSUFFICIENCY]. Risk of magnesium and aluminum accumulation in these patients. It is recommended to use with caution in case of mild to moderate insufficiency (CLcr 30-90 ml / min), and to avoid it in severe insufficiency (CLcr <30 ml / min).

- [DIGESTIVE HEMORRHAGE]. Patients with digestive bleeding should be evaluated, since almagato could mask more severe conditions such as stomach cancer.

- [INTESTINAL MALABSORTION]. The almagate could reduce the absorption of phosphates by forming insoluble complexes. Caution is recommended in patients with intestinal malabsorption processes, diets poor in phosphorus or in [CONVALESCENCE] before the risk of hypophosphatemia.

PATIENT TIPS

- If the symptoms continue or worsen after 14 days of treatment, consult with the doctor and / or pharmacist.

- Take the antacid away with any other oral medication 2-3 h.

- Tell your doctor and / or pharmacist if you experience any of these symptoms:

* Blood in vomit or stool.

SPECIAL WARNINGS

- Evaluate patients who develop digestive hemorrhage of unknown origin.

ALMAX CHEWABLE TABLETS AND INTERACTIONS

- Antiulcer. The increase in pH could reduce the activation of PPIs (eg omeprazole) in the canaliculi of the parietal glands. Avoid association

- Salicylates. The antacids could alkalize the urine, favoring the elimination of salicylate.

In addition to these interactions, it must be taken into account that antacids can interfere in the absorption of any medication administered orally by different mechanisms. It might be advisable to distance the shots 2-3 h.

The following interaction mechanisms have been described:

- Drugs with pH-dependent absorption. Antacids could affect the solubility and subsequent intestinal absorption of drugs in which gastric pH is a limiting factor. In this way, a decrease in the absorption of drugs such as atenolol, azole antifungals, NSAIDs, digoxin, erlotinib, gabapentin, ulipristal has been observed.

- Formation of insoluble chelates. Aluminum can form insoluble complexes with drugs such as quinolones, iron salts or tetracyclines, reducing their absorption.

ALMAX CHEWABLE TABLETS AND PREGNANCY

Animal safety: no data available.

Safety in humans: adequate and well-controlled human studies are not available. The administration of antacids is considered safe during pregnancy, although it is recommended not to administer at high doses or for long periods of time, before the risk of the appearance of systemic effects. It is advisable to reserve its use for those situations in which there are no safer therapeutic alternatives, and the benefits outweigh the possible risks.

Tendinous hyperreflexia has been reported in neonates of mothers who used aluminum and / or magnesium salts during pregnancy.

Effects on fertility: no specific studies have been conducted in humans.

LACTATION

Animal safety: no data available.

Safety in humans: both aluminum and magnesium can be excreted in milk, but due to low intestinal absorption of almagato is not likely to appear in significant quantities. Compatible with breastfeeding as long as low doses are used and for a short period of time.

CHILDREN

Almagato can be used in adolescents from 12 years of age at the same doses as in adults.

The use of antacids in children <12 years is not recommended as they could mask serious symptoms such as appendicitis. In addition, there is a risk of hypermagnesemia or aluminum toxicity in children treated with magnesium and aluminum salts.

ELDERLY

Aluminum could interfere in the absorption of phosphorus and calcium, favoring the appearance of osteoporosis. It is therefore recommended to avoid high doses or prolonged treatments.

Its use is contraindicated in case of Alzheimer's disease, due to the possible relationship of this disease with aluminum.

EFFECTS ON DRIVING

It does not seem to have important effects.

ADVERSE REACTIONS

The effects are mild, transient and infrequent due to its low intestinal absorption.

Adverse reactions are described according to each frequency interval, being considered very frequent (> 10%), frequent (1-10%), rare (0.1-1%), rare (0.01-0.1%) , very rare (<0.01%) or of unknown frequency (can not be estimated from the available data).

- Digestive: frequency unknown [DIARRHEA].

OVERDOSE

Symptoms: no cases have been described. An interference with the absorption of phosphates is expected, and hypophosphatemia and osteomalacia may appear, especially in chronic intoxications.

Measures to be taken: symptomatic treatment.

Almax 500 Mg Prospectus 48 Chewable Tablets