Cristalmina 10 Mg/Ml Topical Spray Solution 25 Ml

ACTION AND MECHANISM

Antiseptic, chlorophenylbiguanidine derivative. It has a relatively broad antibacterial (bacteriostatic) spectrum, with special activity on gram-positive. It is sporostatic. It does not usually induce antimicrobial resistance. It also has fungistatic action (Candida). Its action is relatively slow but it has considerable persistence and residual adhesion.

INDICATIONS

- "1%": [DISINFECTION] of wounds, erosions, [BURNS], [ESCARAS], disinfection of the skin in the preoperative period. Disinfection of the navel of the newborn. Barrier against bacterial infection applied to the hands of health workers (cream). 
- "4%": Pre-operative disinfection of the hands in surgery, antiseptic hand washing in hospitals and pre / post-operative skin antisepsis in patients undergoing surgery. 
- Sprayer: Disinfection of minor burns, small superficial wounds, cracks and chafing.

POSOLOGY

Topical way: 
- 1%: Apply undiluted on the surface to be disinfected, recommending no more than 2 applications / day. Disinfection of the hands of health personnel: pour about 5 ml on the hands, rinse with water and repeat the operation again. 
- 4%: Pre-operative disinfection of the hands in surgery: wet arms and forearms, apply 5 ml and wash for 1 min cleaning nails, rinse and apply another 5 ml for 2 min, rinse and dry. Antiseptic hand wash in hospitals: wet hands and forearms, apply 5 ml and wash for 1 min, rinse and dry. Preoperative skin antisepsis in patients undergoing surgery: the day before, wash with 25 ml from the face and downwards, paying special attention to the areas around the nose, armpits, navel, English and perineum. Rinse and repeat wash with another 25 ml, including hair. Rinse and dry. Repeat the entire process before the next day.Postoperative skin antisepsis in patients undergoing surgery: from the 3rd day of surgery, wash the entire body, excluding the area of ​​surgery, in accordance with the rules set forth above. 
- Sprayer: Apply 1-2 times after washing the wound.

CONTRAINDICATIONS

- Hypersensitivity to the medicine.

PRECAUTIONS

- Do not apply to eyes or ears. In case of accidental application, wash immediately with plenty of water. 
- The solutions will be stored in bottles with glass, rubber or plastic caps (avoid cork). 
- Dilutions must be renewed weekly. Protect from light and heat. 
- Needles and syringes that have been in contact with chlorhexidine solutions should be rinsed in sterile water or saline solution before intra-spinal use. 
- The treated clothes will not be washed with bleach or hypochlorites, because it can produce brown coloration in the tissues, but with household detergents based on sodium perborate.

INTERACTIONS

The action of chlorhexidine is diminished by alkaline pH, presence of organic matter, anionic detergents and tannins. 
The rise in temperature, neutral pH, non-ionic detergents, alcohol and quaternary ammonium salts favor its action. 
May interfere with microbiological trials of antibiotics.

PREGNANCY

FDA Category B. Animal studies have not registered fetal risk. There are no adequate and well-controlled studies in humans. Precautionary use

LACTATION

It is not known if this medicine is excreted with breast milk. No problems have been described in humans, although the possible risk of systemic effects must be taken into account. Precautionary use

CHILDREN

No specific pediatric problems have been described in this age group.

ELDERLY

No specific geriatric problems have been described in this age group.

ADVERSE REACTIONS

Rarely, [CUTANEOUS IRRITATION], [DERMATITIS] or [PHOTOSENSITIVITY REACTIONS], in which case suspend treatment. Instilated in the middle ear can produce [OTOTOXICITY] ([DEAF]), so it is recommended to take precautions in case of perforation of the eardrum to avoid injury to the tissues of the inner ear. There are cases of hemolysis described after accidental ingestion of clohexidine.

Leaflet Cristalmina 10 Mg / Ml Topical Spray Solution 25 Ml

Data Sheet Crystalmina 10 Mg / Ml Topical Spray Solution 25 Ml